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Did you know that the prevalence of obesity and being overweight has tripled over the years worldwide? This incidence has led to novel and interesting interventions for weight loss. One such approach is the emergence of peptides for weight loss. Well, it might be a new term for some of you, but a few of you might have heard some buzz around peptides for weight loss especially if you were keenly researching on new techniques to shed that unwanted weight.
Peptide therapy was initially used by body builders to build lean mass and reduce fat mass. But now peptides for weight loss are becoming an emerging trend, viable for the general population, helping one achieve better health and fitness if used under proper guidance. Without further ado let’s get into the basics of peptides and how it helps you lose weight.
What are peptides?
Peptides are tiny biomolecules, which are made up of amino acids. Just like a string of beads in your necklace, peptides are a string of amino acids. Many strings of peptides together form a protein. In simpler terms, peptides are nothing but a mini version of proteins. They may be incredibly small but can make a big difference in how you look, feel and live.
Role of peptides in our body
Peptides act like a message in our body, for example, if your blood glucose levels are low, the body signals the pancreas to produce a hormone that can release glucose from the liver to bring your blood glucose levels back to normal. So once the peptides (messages) are delivered to the pancreas, they start their function of releasing hormones which can further maintain the blood glucose balance.
So it’s simple, peptides are the messages which are very precise and specific to every organ. And hormones are the end result of these messages.
Peptides can help improve your health and quality of life in many ways like –
- Strengthening your immune system
- Makes you look younger
- Build muscles
- Increase energy
- Enhances cognitive function
- Improves skin and hair growth
- Brightens mood and sharpens memory
- Good quality sleep
- Easy recovery from injuries
- Improves athletic performance
- Heightens libido
- Burn fat and helps you lose weight
Peptide therapy
As we understood that peptides are organ specific, different peptides affect different cells and function differently. They can be specially combined and customized to improve your health and well-being which is known as peptide therapy.
Why do we need peptides for weight loss
As we age, we tend to lose the rhythm of life as there is a significant change in our circadian rhythm, eating habits, exercise routine, etc. Another potential reason for using peptides for weight loss is the progressive decline of a hormone called Growth Hormone by 15%, every decade of adult life.
The Growth hormone’s role is vast in the human body and is associated with
- Healthy metabolism
- Lowering fat accumulation
- Improves heart health
- Increases exercise capacity
- Maintenance of muscles
- Improves cognitive function
Decrease in growth hormone shows increased abdominal and visceral adiposity. Peptides help our body increase the growth hormone production, helping one sustain/correct the metabolic health and helps in burning fat and losing weight.
Best peptides for weight loss and fat loss
- MOTS-C is a peptide found in mitochondria, which helps in metabolic activities throughout the body especially glucose, where it is converted into usable energy. MOTS-C acts as an exercise mimetic, which means that the hormone can stimulate changes normally activated through exercise. Studies show that MOTS-C helps in regulating blood glucose levels by improving insulin sensitivity and lowering insulin resistance. MOTS-C showed positive implication for enhancing fat breakdown, decreases fat gain even on a high fat diet, prevents fat from accumulating in muscle and maintains an overall healthier lifestyle.
Application Mode : Injection
- Tesamorelin is an FDA approved peptide, which is a growth hormone analog. It means that the peptide is similar to the one normally released from the brain. It dramatically increases human growth hormone. It is used to reduce stubborn belly fat or abdominal fat. It reduces inflammation. Improves cognitive function in healthy adults. Lowers insulin resistance and lowers triglyceride levels in healthy people. Improves overall framework of the body.
Application Mode : Injection
- CJC 1295 – is a peptide which stimulates growth hormone secretion and leads to a steady increase of human growth hormone leading to fat loss and muscle growth. It helps in –
- Fat loss, increase lean muscle mass and better lipid profiles
- Promotes deep sleep, which is associated with fat burning, muscle recovery and memory formation
- It works well in combination with Ipamorelin for accelerated fat loss and promotes lean body mass
Application Mode : Injection
- Ipamorelin is a class of peptides which helps the body to produce more of growth hormone. Its uses are –
- Accelerates fat loss
- Improves sleep, mood and energy
- Improves muscle strength and mass
- Improves long term growth hormone production
Application Mode : Injection and oral troche
- Sermorelin is a peptide which fights the effects of aging and promotes weight loss, by stimulating the natural production of human growth hormone which declines over age. Its uses are –
- Improves your appearance
- Increases lean muscle mass
- Reduces body fat
- Enhances quality of sleep
- Improves skin firmness and thickness
- Reduces body aches and muscle aches
Application Mode : Injection, oral troche, Oral capsules
- MK-677 (ibutamoren) is a peptide that stimulates the naturally stored growth hormones for the body to use. It –
- Increases growth hormone levels
- Builds muscle mass
- Increases muscle strength
- Improves fat burning
- Accelerates weight loss
- Revs up metabolism
- Enhances sleep quality
- Regenerates nerve tissue
- Improves cognition
Application Mode : Oral capsule ( doesn’t come in injection)
- AOD 9604 is a fragment of the human growth hormone. This peptide helps in stimulating the metabolism. It –
- Boosts fat loss and burns calories
- Decreases the extra fat from the obese cells more than lean cells
- Helps in reducing belly fat
- Destroys stored fat cells
- Works wonderfully without affecting your hunger or blood sugar levels
Application Mode : Injection and oral troche
Combination of Peptides for weight loss and fat loss
Combination of peptides have proven to show better results than single peptides
- CJC 1295 + Ipamorelin – This combination proves that two is better than one for restoring youth and vitality. When this combination is carefully combined the body is able to produce stronger and steadier release of the growth hormone to provide twice the fitness and weight loss benefits. It helps in –
- Enhancing fat loss and weight loss
- Increasing lean muscle mass
- Enhancing sleep quality
- Enhancing energy levels and stamina
Application Mode : Injection and oral troche
- IGF-1 LR3, CJC 1295 + Ipamorelin – This unique blend provides optimum human growth hormone production in the body. Its main function is to build new muscle tissues by promoting nitrogen retention and protein synthesis. It –
- Increases metabolic expenditure
- Improves healing and recovery
- Improves fat loss and weight loss
- Increases lean muscle mass
- Fights inflammation and arthritis
Application Mode : Injection
How fast can I see results from Peptides for weight loss?
Results are dependent on many factors like age, the dosage, if you have any medical condition and the lifestyle you follow. Results vary from 3 months to 6 months depending on the type of peptide used, for e.g. Ipamorelin is more gentle and it takes 3-6 months to see significant changes, increases at 6 months and sustained for 12 months. But if you’re all set and follow a perfect routine with Tesamorelin you can notice significant changes within a few weeks.
Let me give you a word of caution, you need to take peptides only under the supervision of a medical practitioner as a part of your weight loss program. Speak to your doctor about the dose and right kind of peptide based on your goals.
Apart from that you need to manage your diet and cook your own food so you can control what you’re eating. Remember great abs are made in the kitchen!
So you need to use it correctly with your diet, exercise and sleep. If used incorrectly peptides have the potential to cause various side effects
Side effects of peptides for weight loss
For healthy individuals peptide injections are unlikely to cause serious side effects because they are similar to the peptides present in everyday foods. But if you have any pre-existing medical conditions you could be at risk of side effects like
- Itchiness at the injection area
- Increased water retention (common sign of overdose)
- Increased hunger
- Dry mouth
- Tingling or numbness
Peptides for weight loss has been shown to help people fight off their excess stubborn weight and fat with a number of health benefits. Though peptide therapy is known to be one of the wonderful slimming solutions, it can be more sustainable when combined with a low-calorie diet, exercise, and simple lifestyle modifications.
Research shows that people lose up to 60-75 pounds (i.e., 25-34 kgs) when peptide therapy is combined with healthy eating habits and lifestyle modifications. Amazing right?
So, before you choose peptides for weight loss, it’s advisable to consult your medical practitioner and take advice from them.
NOTE: Do not to use peptides on your own as you might end up with other consequences.
Written by Aishwarya Deepika, ENHAPP Wellness Coach & Nutritionist